See also this list of medicines that have codeine and read the consumer information and facts medicine (CMI) leaflet for your brand name prescribed, or:
Lung Difficulties. Promethazine/phenylephrine/codeine really should not be employed Should you have intense bronchial asthma, hassle respiration, or other lung challenges. Promethazine/phenylephrine/codeine may make these ailments even worse.
Extensive-time period use of promethazine/phenylephrine/codeine may possibly have an impact on your capability to become Expecting or get yourself a lover Expecting. Talk to your Health care supplier When you've got any concerns.
opioid receptors distributed through the central anxious program. The sedative routines of codeine are a lot less strong than Those people of morphine eighteen. Codeine may cause respiratory system melancholy with the activation of μ-opioid receptors at certain websites during the central anxious technique 8.
Manitoba Pharmacists usually are not permitted to fill US physicians’ prescriptions. They are able to only fill prescriptions issued by a health practitioner licensed inside of a province or territory of copyright. CPhM takes the place that it might be contrary to professional requirements for a pharmacist to fill prescriptions by a health practitioner, accredited inside of a province or territory of copyright, who may have not founded an appropriate individual-medical professional romantic relationship along with you.
Never drink Liquor or use prescription or over-the-counter medicines that have Liquor. Utilizing Liquor when taking promethazine/phenylephrine/codeine can result in you to definitely overdose and die.
Sphincter of Oddi Spasm. The sphincter of Oddi is often a muscular valve in Your entire body that controls the movement of bile and digestive juices from the pancreas to the compact intestine. When this valve spasms, it might come to feel like obtaining a tight muscle cramp, producing discomfort and blocking the movement of these juices, which can result in soreness and digestive issues.
Breastfeeding is not suggested for the duration of remedy with codeine or tramadol because the medicine passes through breast milk and will hurt the newborn.
Maternally harmful doses which were about seven periods the most advised human dose of 360 mg/working day, have been linked to proof of bone resorption and incomplete bone ossification. Codeine didn't show proof of embrytoxicity or fetotoxicity in the rabbit product at doses nearly 2 moments the most advisable human dose of more info 360 mg/working day depending on a human body surface place comparison Label. Nonteratogenic results
into the tramadol label warning versus its use in young children youthful than 18 yrs to take care of ache just after surgery to remove the tonsils and/or adenoids.
Postmarketing cases of respiratory depression, which includes fatalities, havebeen documented with use of promethazine hydrochloride in pediatric patientsless than 2 several years of age. A variety of pounds-based doses ofpromethazine hydrochloride have resulted in respiratory melancholy inthese clients.
This mixture medication is accustomed to enable minimize mild to reasonable suffering. It has an opioid discomfort reliever (codeine) and a non-opioid pain reliever (acetaminophen). Codeine operates within the brain to alter how The body feels and responds to pain. Acetaminophen may lessen a fever. See Additional
Pregnancy. Promethazine/phenylephrine/codeine could bring about damage to an unborn baby. Inform your Health care company For anyone who is or strategy to be pregnant. Your Health care supplier will advise you if you need to take promethazine/phenylephrine/codeine when you are Expecting or endeavoring to get Expecting.
Resuscitation may very well be required (see OVERDOSAGE). Limited information recommend that use of promethazine hydrochloride in the course of labor and shipping and delivery does not have an appreciable impact on the period of labor or shipping and won't increase the risk of will need for intervention during the newborn.